Research
Trends and correlation between antimicrobial usage and resistant pattern in Malaysia
This is an observational study aiming to evaluate the trend in antimicrobial utilisation and antimicrobial resistance in Malaysian hospitals setting, using WHONET antimicrobial surveillance data.
Costs, Readmission and Mortality Evaluation of Drug-Resistant Mycobacterium Tuberculosis in Malaysia - (CoMET)
This study aims to evaluate the cost of illness, hospital readmission, and mortality associated with drug-resistant tuberculosis (DR-TB) from 2020 to 2023. Specifically, it seeks to quantify both direct and excess treatment costs, estimate hospital readmission and in-treatment mortality rates, and examine their associated factors.
Drug Resistant Tuberculosis in Malaysia: A Retrospective Cohort Study
This is a retrospective, registry-based study. It evaluates the incidence and cascade of care for individuals with DR-TB in Malaysia from 2020 to 2023. The study also investigates the factors associated with treatment outcomes.
Latent Tuberculosis Infection in Malaysia: A Cohort Analysis (MY-LTBI)
This retrospective cohort study evaluated the cascade of care for latent tuberculosis infection (LTBI) in Malaysia using national surveillance data from 2021–2022. It examined the cascade of care of LTBI and the determinants of tuberculosis preventive treatment non-initiation and non-completion.
Evaluating the Effectiveness of Tuberculosis Preventive Treatment on Tuberculosis Incidence Among Latent Tuberculosis Infection Cases in Malaysia: A Cohort Study (TPT-LTBI)
This retrospective cohort study evaluates the effectiveness of Tuberculosis Preventive Treatment (TPT) in Malaysia by comparing tuberculosis (TB) incidence among individuals with latent tuberculosis infection (LTBI) who completed TPT with those who did not initiate or complete TPT, using linked national registry data.
Evaluation of the Outpatient Parenteral Antimicrobial Therapy (OPAT) Service in Malaysia
This study employs mixed qualitative and quantitative methods to examine the provision of the OPAT service in thirteen selected public hospitals in Malaysia. It consists of four distinct parts; a scoping review, cohort analysis, patients’ satisfaction and providers’ experience.
Readmissions, Mortality and Cost associated with Antimicrobial Resistance in Malaysia (RACE)
This is a multicentre, retrospective cohort study (2022–2024) using a parallel paired cohort design. It examines the burden of drug-resistant infections by exploring their epidemiology, determining the excess mortality and hospital readmission rates, identifying factors influencing these outcomes, and estimating the excess hospitalisation costs associated with them.
Impact Evaluation of Policies and Guidelines on Antibiotic Consumption in Primary Care
This is an interrupted time series (ITS) study aiming to evaluate the impact of the various policies and guidelines in place for implementation of prudent and rational antibiotic prescribing in Malaysian public primary care setting.